Topical steroid, cyclosporin A, and the outcome of rat corneal allografts.

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منابع مشابه

Topical steroid, cyclosporin A, and the outcome of rat corneal allografts.

The effects of a combination of topical corticosteroid and cyclosporin A on corneal graft survival were tested in a model of penetrating keratoplasty in the inbred rat. Topical medications were applied four times daily to the graft for 28 days postgraft. Neither topical steroid (1% prednisolone acetate) nor topical cyclosporin (1% in chremophor EL/ethanol) was able to modify the overall inciden...

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Rabbit corneal allograft survival following topical administration of cyclosporin A.

Cyclosporin A (CS-A), selectively inhibited cellular immunity, delayed the skin graft-induced rejection of corneal allografts in rabbits when administered subconjunctivally in the dose of 3 mg/kg/day or in the form of 5% water-soluble drops five times daily for 28 days. The subconjunctival application of CS-A was irritating, whereas the topical instillation of the water-soluble preparation was ...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1987

ISSN: 0007-1161

DOI: 10.1136/bjo.71.3.239